Principal investigator2016
Name: Jie CUI Gender:
Education:  2008-2011, Ph.D., East China Normal University
Academic degree: Ph.D Academic title: Principal Investigator
Departments: Pathogen Bioinformatics Unit Discipline: Microbiology
Phone: 021-54923135 E-mail:
Mailing Address: Life Science Research Building, 320 Yueyang Road, Xuhui District, 200031

Curriculum vitae:

2019-present, Principal investigator, Institut Pasteur of Shanghai, CAS
2014-2016, Research Fellow, Duke-NUS Graduate Medical School
2012-2013, Postdoctoral fellow, The University of Sydney

2011-2012, Postdoctoral Researcher, The Pennsylvania State University


Research direction:

Research Focus

1.       Endogenous retroviruses/retroelements & diseases

2.       Exploring virosphere/virome

3.       Evolutionary occurrence of pathogenicity

4.       Evolution and molecular epidemiology of emerging infectious diseases


Research progress:

Selected Publications (*Corresponding author)

1.      Chen Y, Zhang YY, Wei X, Cui J*. (2021) Multiple infiltration and cross-species transmission of foamy viruses across Paleozoic to Cenozoic era. J Virol. 92:e00921-17. Online ahead of print.

2.      Zhang YY, Chen Y, Wei X, Cui J*. (2021) Viromes in marine ecosystems reveal remarkable invertebrate RNA virus diversity. Sci China Life Sci. 64,

3.      Tang X, Wu C, Li X, Song Y, Yao X, Wu X, Duan Y, Zhang H, Wang Y, Qian Z, Cui J*, Lu J*. (2020) On the origin and continuing evolution of SARS-CoV-2. Natl Sci Rev. 7:1012-1023.

4.      Wei X, Li X, Cui J*. (2020) Evolutionary perspectives on novel coronaviruses identified in pneumonia cases in China. Natl Sci Rev. 7:239-242.

5.      Chen M, Tachedjian M, Marsh GA, Cui J*, Wang LF*. (2020) Distinct Cell Transcriptomic Landscapes Upon Henipavirus Infections. Front Microbiol. 11:986.

6.      Chen Y, Wei X, Zhang G, Holmes EC, Cui J*. (2019) Identification and evolution of avian endogenous foamy viruses. Virus Evol. 5:vez049.

7.      Wei X, Chen Y, Duan G, Holmes EC, Cui J*. (2019) A reptilian endogenous foamy virus sheds light on the early evolution of retroviruses. Virus Evol. 5:vez001.

8.      Cui J, Li F, Shi ZL*. (2019) Origin and evolution of pathogenic coronaviruses. Nature Rev Microbiol. 17:181-192.

9.      Wei X, Chen M, Cui J*. (2017) Bayesian evolutionary analysis for emerging infectious disease: an exemplified application for H7N9 avian influenza viruses. Sci China Life Sci. 60:1392-1395.

10.   Hu B, Zeng LP, Yang XL, Ge XY, Zhang W, Li B, Xie JZ, Shen XR, Zhang YZ, Wang N,Luo DS, Zheng XS, Wang MN, Daszak P, Wang LF, Cui J*, Shi ZL*. (2017) Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus. PLoS Pathog. 13:e1006698.

11.   Wang H, Zhao Y, Chen M*, Cui J*. (2017) Identification of Novel Long Non-coding and Circular RNAs in Human Papillomavirus-Mediated Cervical Cancer. Front Microbiol. 8:1720.

12.   Du Y, Chen M, Yang J, Jia Y, Han S, Holmes EC, Cui J*. (2017) Molecular evolution and emergence of H5N6 avian influenza virus in central China. J Virol. 91:e00143-17.


Laboratory members:

Research Associate/Assistant: Zixuan Han; Yicong Chen; Meng Ren

Ph.D. Candidates: Xiaojing Wang; Meng’en Liao; Yian Li; Xiang Li