专家人才库数据----中国科学院上海巴斯德研究所

Principal investigator2016

Name:	Suihan FENG	Gender:
Education:	2014, Ph.D., EMBL Heidelberg.
Academic degree:	Ph.D.	Academic title:	Principal Investigator
Departments:	Chemical Biology and Lipid Metabolism	Discipline:	Chemical Biology
Phone:		E-mail:	suihan.feng@ips.ac.cn
Mailing Address:	Life Science Research Building, 320 Yueyang Road, Xuhui District, 200031

Curriculum vitae:
Suihan Feng obtained his PhD from EMBL Heidelberg in 2014. He moved to Howard Riezman laboratory at the University of Geneva in 2015. In June 2021, He joined the Institut Pasteur Shanghai (IPS), Chinese Academy of Science (CAS) and started to work in his own lab.

Research direction:
Lipids are fundamentally important in all life forms, but many basic questions about lipids are not answered due to the lack of available techniques. Our lab is interested in combining the skills of synthetic chemistry, biochemistry and cell biology to uncover new principles and mechanisms regulating local lipid metabolism and transport. We are also keen on translating acquired knowledge to advance our understanding of lipids during the host-microbiota interactions.

Research direction:

Lipids are fundamentally important in all life forms, but many basic questions about lipids are not answered due to the lack of available techniques. Our lab is interested in combining the skills of synthetic chemistry, biochemistry and cell biology to uncover new principles and mechanisms regulating local lipid metabolism and transport. We are also keen on translating acquired knowledge to advance our understanding of lipids during the host-microbiota interactions.

Research progress:
Selected Publications *(^First author, ^#Corresponding author) S Feng**; T Harayama; D Chang; JT Hannich; N Winssinger; H Riezman, Lysosome targeted photoactivation reveals local sphingosine metabolism signature. Chem. Sci.* 2019; 10, 2253-2258 (cover picture, featured as 2019 Chemical Science HOT Article Collection) S Feng; T Harayama; S Montessuit; F David; N Winssinger; JC Martinou; H Riezman, Mitochondria-specific photoactivation to monitor local sphingosine metabolism and functions. eLife* 2018; 7, e34555 M Schifferer; S Feng*; F Stein; C Tischer; C Schultz, Reversible chemical dimerizerinduced recovery of PIP2 levels moves clathrin to the plasma membrane. Bioorg. Med. Chem., 2015, 23, 2862-2867. (co-first author) S Feng; V Laketa; F Stein; A Rutkowska; A MacNamara; S Depner; U Klingmueller; J Saez-Rodriguez; C Schultz, A rapidly reversible chemical dimerizer system to study lipid signalling in living cells. Angew. Chem. Int. Ed., 2014, 53, 6720-6723 (selected as a VIP paper, featured in ChemBioChem)

Research progress:

Selected Publications (^*First author, ^#Corresponding author)

S Feng*; T Harayama; D Chang; JT Hannich; N Winssinger; H Riezman, Lysosome targeted

photoactivation reveals local sphingosine metabolism signature. Chem. Sci. 2019; 10, 2253-2258 (cover picture, featured as 2019 Chemical Science HOT Article Collection)

S Feng*; T Harayama; S Montessuit; F David; N Winssinger; JC Martinou; H Riezman,

Mitochondria-specific photoactivation to monitor local sphingosine metabolism and functions.

eLife 2018; 7, e34555

M Schifferer*; S Feng*; F Stein; C Tischer; C Schultz, Reversible chemical dimerizerinduced

recovery of PIP2 levels moves clathrin to the plasma membrane. Bioorg. Med. Chem., 2015, 23, 2862-2867. (*co-first author)

S Feng; V Laketa; F Stein; A Rutkowska; A MacNamara; S Depner; U Klingmueller; J

Saez-Rodriguez; C Schultz, A rapidly reversible chemical dimerizer system to study lipid

signalling in living cells. Angew. Chem. Int. Ed., 2014, 53, 6720-6723 (selected as a VIP

paper, featured in ChemBioChem)

Laboratory members:
Positions available (Students, Technicians, Research assistant or Postdoc).