白念珠菌碱化外界环境pH分子机制;白念珠菌蛋白核质转运机制;隐球菌突破宿主血脑屏障分子机制。
代表性论文(Representative paper):
1). Yu J#, Tran V#, Li M, Huang X, Niu C, Wang D, Zhu J, Wang J, Gao Q*, Liu J*. (2012) Both phthiocerol dimycocerosates and phenolic glycolipids are required for virulence of Mycobacterium marinum. Infect Immun, 80(4):1381-1389
2) Huang X, Wang H, Meng L, Wang Q, Yu J, Gao Q, Wang D*. (2016) Role of eosinophils and apoptosis in PDIMs/PGLs deficient mycobacterium elimination in adult zebrafish. Dev Comp Immunol, 59: 199-206.
3) Huang X#, Chen X#, He Y#, Yu X, Li S, Gao N, Niu L, Mao Y, Wang Y, Wu X, Wu W, Wu J, Zhou D, Zhan X, Chen C*. (2017) Mitochondrial complex I bridges a connection between regulation of carbon flexibility and gastrointestinal commensalism in the human fungal pathogen Candida albicans. PLOS Pathogens, 13(6): e1006414.
4) Chen C* and Huang X. (2018) Chapter 10: Candida albicans Commensalisms and Human Diseases. Ed. Jun Sun and Dudeja PK, Book title: Mechanisms Underlying Host- Microbiome Interactions in Pathophysiology of Human Diseases. Springer Nature.
5) Tian Y#, Gao N#, Ni Q, Mao Y, Dong D, Huang X, Jiang C, Li Z, Zhang L, Wang X, Peng Y* and Chen C*. (2018) Sequence modification of the master regulator Pdr1 interferes with its transcriptional autoregulation and confers altered azole resistance in Candida glabrata. FEMS Yeast Research, 18(4).
6) 专利: 陈昌斌, 何永明,陈晓庆,李姗姗,羽晓瑜,黄新华, 高宁. (2017) “调控微生物生物被膜形成的基因靶点及其应用”, 申请号: 201610255477.3