Principal Investigators

Principal Investigators
Name: Nicolas BERTHET
Unit Name: Unit of Discovery and Molecular Characterization of Pathogens
Education(CV):

2019             Habilitation à Diriger des Recherches (HDR), University of Denis Diderot, Paris VII

2014             Bio-informatic “NGS and Cancer”, Cancérop?le, Paris, France

2011             Genome analysis training, Institut Pasteur, Paris, France

2008             Systematic virology training, Institut Pasteur, Paris, France

2004-2007    Ph .D. Degree in Microbiology (PhD), University of Denis Diderot, Paris VII

2003             Phamacy Degree. University of Grenoble, Grenoble, France

2003             Master of Molecular and Cellular Biology, University of Grenoble, Grenoble, France

1996-2003    School of Pharmacy, 12th at the admission competitive examination, University of Grenoble, Grenoble, France

1996             Baccalaureat in Sciences, High School, Bonneville, France

Email: nicolas.berthet@ips.ac.cn

Research Topic:

The first research axis of this unit will be the discovery and molecular characterization of pathogens from primary samples based on the use of different high throughput sequencing technologies. The second axis will be the search for prognostic markers to anticipate the progression of precancerous lesions to malignancy for cervical cancer. Finally, this research unit will also provide the other research teams at the centre with access to the various high-throughput sequencing technologies for bacterial and/or viral metagenomic research projects.

Unit logo: 

Team Members:

Nicolas BERTHET: Principal Investigator

Yawen TIAN: Lab Manager

Kathrina Mae BIENES: Postdoctoral Fellow

Meriem FASSATOUI: Postdoctoral Fellow

Alex Augusto ARMERO VILLANUEVA: Special Research Assistant

Victor OMONDI: MS student

Lingjing MAO: MS-PhD student

Jiaxu YING: MS-PhD student

 

Selected Bibliography :

1. Berthet N, Leclercq I, Dublineau A, Shigematsu S, Burguière AM, Filippone C, Gessain A, Manuguerra JC. Highdensity resequencing DNA microarrays in public health emergencies. Nat Biotechnol. 2010 Jan;28(1):25-7.
2. Berthet N, Nakouné E, Whist E, Selekon B, Burguière A-M, Manuguerra J-C, Gessain A, Kazanji M. Maculopapular lesions in two young Pygmies in the Central African Republic. 2011. Lancet. 2011 Oct 8;378(9799):1354.
3. *Maganga G.D., *Bertherat E., *Berthet N., Briand S., Cabore J., Epelboin A., Formenty P., González-Angulo L., Kebela Ilunga B., Kabange F., Mondonge V., Tamfum Muyembe J.J., Okwo-Bele J.M., Labouba I., Manuguerra J.C., Dye C., Phil D., Leroy E.M. Ebola Virus Disease in the Democratic Republic of Congo. N Engl J Med. 2014 Oct 15.
4. Simo Tchetgna H, Sem Ouilibona R, Nkili-Meyong AA, Caron M, Labouba I, Selekon B, Njouom R, Leroy EM, Nakoune E, Berthet N. Viral Exploration of Negative Acute Febrile Cases Observed during Chikungunya Outbreaks in Gabon. Intervirology. 2019 Jan 9:1-11.